CARD18
Function
Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.
Tissue Specificity
Primarily expressed in the heart and placenta.
Alternative names
ICEBERG, UNQ5804/PRO19611, CARD18, Caspase recruitment domain-containing protein 18, Caspase-1 inhibitor Iceberg