Catalase

Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide (PubMed:7882369). Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells (PubMed:7882369).

Acatalasemia

ACATLAS

A metabolic disorder characterized by a total or near total loss of catalase activity in red cells. It is often associated with ulcerating oral lesions. Acatalasemia is inherited as an autosomal recessive trait.

None

The disease is caused by variants affecting the gene represented in this entry.

Belongs to the catalase family.

• Peroxisome matrix

Catalase, CAT

• entrezGene:847
• omim:115500
• swissprot:P04040

Proteins

Metabolism

59756Da