Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (PubMed:12782676). Has also been implicated in tumor invasion and metastasis (By similarity).
Belongs to the peptidase C1 family.
Expressed in thyroid epithelial cells.
Cathepsin B, Cathepsin B1, Ctsb
Proteins
Neuroscience
37280Da
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ab119585