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Function

Chemotactic for activated T-lymphocytes. May play an important role in the collaboration of dendritic cells and B-lymphocytes with T-cells in immune responses.

Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.

Tissue specificity

Expressed by activated splenic B-lymphocytes and dendritic cells. Low expression in lung, thymocytes, lymph node, and unstimulated splenic cells.

Cellular localization

  • Secreted

Alternative names

Abcd1, Scya22, Ccl22, C-C motif chemokine 22, Activated B and dendritic cell-derived, CC chemokine ABCD-1, Small-inducible cytokine A22

Target type

Proteins

Primary research area

Immuno-oncology

Molecular weight

10302Da

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