Ccl28
Function
Chemotactic for resting CD4, CD8 T-cells and eosinophils (By similarity). Binds to CCR10 and induces calcium mobilization in a dose-dependent manner.
Sequence Similarities
Belongs to the intercrine beta (chemokine CC) family.
Tissue Specificity
Mainly expressed in testis, epithelial cells of normal colon, kidney, Peyer patches, lymph nodes. Also found in lower levels in brain, spleen and lung.
Cellular localization
- Secreted
Alternative names
Scya28, Ccl28, C-C motif chemokine 28, Small-inducible cytokine A28