CCL7

Function

Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.

Post-translational modifications

O-glycosylated.

Sequence Similarities

Belongs to the intercrine beta (chemokine CC) family.

Cellular localization

• Secreted

Alternative names

MCP3, SCYA6, SCYA7, CCL7, C-C motif chemokine 7, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, Small-inducible cytokine A7, MCP-3

Database links

swissprot:P80098 entrezGene:6354 omim:158106

Other research areas

• Immunology & Infectious Disease