CCR9

Function

Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.

(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.

Sequence Similarities

Belongs to the G-protein coupled receptor 1 family.

Tissue Specificity

Highly expressed in the thymus and low in lymph nodes and spleen.

Cellular localization

• Cell membrane
• Multi-pass membrane protein

Alternative names

CDw199, GPR28, CCR9, C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6

Database links

swissprot:P51686 omim:604738 entrezGene:10803

Other research areas

• Immuno-oncology