CCT3

Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).

Belongs to the TCP-1 chaperonin family.

• Cytoplasm

CCTG, TRIC5, CCT3, T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma, Chaperonin containing T-complex polypeptide 1 subunit 3, hTRiC5

• entrezGene:7203
• omim:600114
• swissprot:P49368

Proteins

Neuroscience

60534Da