Sialomucin core protein 24

During embryogenesis, expression in found in all stages examined, with the highest levels of expression at early stages (8.5 dpc) and moderate levels of expression being found at mid- to late stages of embryogenesis. Expressed during early stages of skeletal muscle development. At embryonic stages 9.5 dpc and 10.5 dpc, expressed strongly in the dorsal somite (the structure of origin for skeletal muscle precursors). It is also expressed at later stages of muscle development;.

Sialomucin that may play a key role in hematopoiesis. May be involved in cell adhesion (By similarity). Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes.

Highly N- and O-glycosylated; contains sialic acid.

Belongs to the CD164 family.

Expressed at high levels in the submaxillary gland and kidney, at moderate levels in the brain, heart, lung, liver, intestine, testis, muscle and bone marrow, and at low levels in the pancreas, spleen and thymus. In the ear, expressed in the inner and outer hair cells of the organ of Corti, cells of Kolliker's organ, cells in the lateral cochlear wall behind the spiral prominence and cells of the stria vascularis (PubMed:26197441).

• Lysosome membrane
• Single-pass type I membrane protein
• Endosome membrane
• Single-pass type I membrane protein
• Cell membrane
• Single-pass type I membrane protein

CD164, Sialomucin core protein 24, MUC-24, Endolyn, Multi-glycosylated core protein 24, MGC-24, MGC-24v, Cd164

• entrezGene:53599
• swissprot:Q9R0L9

Proteins

Oncology

21059Da