CD1B
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Tissue Specificity
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
- Endosome membrane
- Single-pass type I membrane protein
- Lysosome membrane
- Single-pass type I membrane protein
- Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Alternative names
CD1b, T-cell surface glycoprotein CD1b, CD1B