CD1C

Function

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

Tissue Specificity

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein
• Endosome membrane
• Single-pass type I membrane protein
• Lysosome
• Subject to intracellular trafficking between the cell membrane and endosomes.

Alternative names

CD1c, T-cell surface glycoprotein CD1c, CD1C

Database links

swissprot:P29017 omim:188340 entrezGene:911

Other research areas

• Immuno-oncology