CD1D

Function

Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.

Tissue Specificity

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein
• Basolateral cell membrane
• Single-pass type I membrane protein
• Endosome membrane
• Single-pass type I membrane protein
• Lysosome membrane
• Single-pass type I membrane protein
• Endoplasmic reticulum membrane
• Single-pass type I membrane protein
• Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.

Alternative names

CD1d, Antigen-presenting glycoprotein CD1d, R3G1, CD1D

Database links

swissprot:P15813 entrezGene:912 omim:188410

Other research areas

• Immuno-oncology