CD2

CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

Expressed in natural killer cells (at protein level).

• Cell membrane
• Single-pass type I membrane protein

CD2, SRBC, T-cell surface antigen CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5

• entrezGene:924
• entrezGene:914
• omim:186820
• omim:186990
• swissprot:P06729
• swissprot:P09564

Proteins

Immunology & Infectious Disease

• Immuno-oncology

39448Da