Cd200r1
Function
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli (By similarity).
Post-translational modifications
Phosphorylated on tyrosine residues.
Highly N-glycosylated.
Sequence Similarities
Belongs to the CD200R family.
Tissue Specificity
Restricted to cells of the myeloid lineage.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
Alternative names
Mox2r, Ox2r, Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, OX102 antigen
Database links
Other research areas
- Immunology & Infectious Disease