CD27

Function

Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

Tissue specificity

In thymus and spleen, but not in non-lymphoid tissues.

Cellular localization

• Membrane
• Single-pass type I membrane protein

Alternative names

• CD27 antigen
• CD27L receptor
• T-cell activation antigen CD27
• Tumor necrosis factor receptor superfamily member 7
• Tnfrsf7
• Cd27

Database links

• entrezGene:21940
• swissprot:P41272

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Other research areas

• Immuno-oncology

Molecular weight

28164Da