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Function

Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (PubMed:12881420).

Cellular localization

  • Isoform I
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform III
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform IV
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform V
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform II
  • Secreted

Alternative names

CD40, Tnfrsf5, Cd40, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor

Target type

Proteins

Primary research area

Immuno-oncology

Other research areas

  • Immunology & Infectious Disease
  • Neuroscience

Molecular weight

32093Da

We found 21 products in 4 categories

Primary Antibodies

Assay Kits

Target

Reactive species

Detection method

Proteins & Peptides

Target

Species of origin