CD5

Function

May act as a receptor in regulating T-cell proliferation.

Post-translational modifications

Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein

Alternative names

• T-cell surface glycoprotein CD5
• Lymphocyte antigen T1/Leu-1
• LEU1
• CD5

Database links

• entrezGene:921
• entrezGene:931
• omim:153340
• omim:112210
• swissprot:P06127
• swissprot:P11836

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Other research areas

• Immuno-oncology

Molecular weight

54578Da