Cd53
Function
Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).
Sequence Similarities
Belongs to the tetraspanin (TM4SF) family.
Tissue Specificity
Spleen and thymus, B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes, peripheral T-cells.
Cellular localization
- Cell membrane
- Cell junction
- Membrane
- Multi-pass membrane protein
- Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.
Alternative names
CD53, Ox-44, Cd53, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Leukocyte antigen MRC OX-44