CD53

Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).

Belongs to the tetraspanin (TM4SF) family.

Spleen and thymus, B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes, peripheral T-cells.

• Cell membrane
• Cell junction
• Membrane
• Multi-pass membrane protein
• Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.

CD53, Ox-44, Cd53, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Leukocyte antigen MRC OX-44

• entrezGene:24251
• swissprot:P24485

Proteins

Immuno-oncology

24168Da