Cd7
Function
Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of gamma-interferon levels.
Cellular localization
- Membrane
- Single-pass type I membrane protein
Alternative names
CD7, T-cell antigen CD7, Cd7