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Function

ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity).

Sequence similarities

Belongs to the CDC123 family.

Tissue specificity

Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.

Cellular localization

  • Cytoplasm

Alternative names

C10orf7, D123, CDC123, Translation initiation factor eIF2 assembly protein, Cell division cycle protein 123 homolog, HT-1080, PZ32, Protein D123

Target type

Proteins

Molecular weight

39135Da

We found 8 products in 2 categories

Primary Antibodies

Target

Reactive species

Proteins & Peptides

Target

Species of origin