CDC123
Function
ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity).
Sequence Similarities
Belongs to the CDC123 family.
Tissue Specificity
Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.
Cellular localization
- Cytoplasm
Alternative names
C10orf7, D123, CDC123, Translation initiation factor eIF2 assembly protein, Cell division cycle protein 123 homolog, HT-1080, PZ32, Protein D123