CDC42BPG
Function
May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity).
Sequence Similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
Tissue Specificity
Expressed in heart and skeletal muscle.
Cellular localization
- Cytoplasm
- Concentrates at the leading edge of cells.
Alternative names
DMPK2, CDC42BPG, Serine/threonine-protein kinase MRCK gamma, CDC42-binding protein kinase gamma, DMPK-like gamma, Myotonic dystrophy kinase-related CDC42-binding kinase gamma, Myotonic dystrophy protein kinase-like alpha, MRCK gamma, MRCKG, Myotonic dystrophy protein kinase-like gamma