CDKN2C
Function
Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
Sequence Similarities
Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Tissue Specificity
Highest levels found in skeletal muscle. Also found in pancreas and heart.
Alternative names
CDKN6, CDKN2C, Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6