CEACAM20
Function
Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response.
Post-translational modifications
Phosphorylated on tyrosine residues by SYK, SRC and FYN in vitro.
Sequence Similarities
Belongs to the immunoglobulin superfamily. CEA family.
Cellular localization
- Cell projection
- Microvillus membrane
- Single-pass type I membrane protein
- Apical cell membrane
- Single-pass type I membrane protein
- Colocalizes with PTPRH and CEACAM1 at the apical brush border of intestinal cells.
Alternative names
UNQ9366/PRO34155, CEACAM20, Cell adhesion molecule CEACAM20, Carcinoembryonic antigen-related cell adhesion molecule 20, CEA cell adhesion molecule 20