Ceacam5
Function
Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.
Sequence Similarities
Belongs to the immunoglobulin superfamily. CEA family.
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
- Apical cell membrane
- Cell surface
- Localized to the apical glycocalyx surface.
Alternative names
Psg30, Cell adhesion molecule CEACAM5, Carcinoembryonic antigen-related cell adhesion molecule 5, Pregnancy-specific glycoprotein 30, CEA cell adhesion molecule 5, CD66e