CEMP1
Function
May play a role in development of the periodontium which surrounds and supports the teeth by promoting the differentiation of multi-potent cells from the periodontal ligament into cementoblasts to form the cementum (PubMed:17509525, PubMed:21465469, PubMed:21929512). Binds hydroxyapatite and may promote the biomineralization of the cementum (PubMed:19393626). Also promotes cell proliferation (PubMed:17509525, PubMed:21929512, PubMed:26011628).
Post-translational modifications
Phosphorylated.
N-glycosylated.
Tissue Specificity
Expressed by cementoblasts, a subpopulation of periodontal ligament cells and cells located around vessels in periodontium (at protein level).
Cellular localization
- Cytoplasm
- Nucleus
- Localizes to the nucleus of some cementoblasts.
Alternative names
Cementoblastoma-derived protein 1, Cementum protein 1, Cementum protein 23, CP-23, CEMP1