CENPP
Function
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
Sequence Similarities
Belongs to the CENP-P/CTF19 family.
Cellular localization
- Nucleus
- Chromosome
- Centromere
- Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Alternative names
Centromere protein P, CENP-P, CENPP