CEP170
Function
Plays a role in microtubule organization (PubMed:15616186). Required for centriole subdistal appendage assembly (PubMed:28422092).
Post-translational modifications
Phosphorylated; probably by PLK1.
Sequence Similarities
Belongs to the CEP170 family.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Centriole
- Cytoplasm
- Cytoskeleton
- Spindle
- Associated with the mature mother centriole. Associated with spindle microtubules during mitosis. Localizes to the distal appendage region of the centriole (PubMed:31789463). Localizes at the centriole proximal ends (PubMed:31789463).
Alternative names
FAM68A, KAB, KIAA0470, CEP170, Centrosomal protein of 170 kDa, Cep170, KARP-1-binding protein, KARP1-binding protein