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Function

Involved in the biogenesis of cilia (PubMed:20551181). Required for the recruitment of PLK1 to centrosomes and S phase progression (PubMed:24018379).

Sequence similarities

Belongs to the CEP43 family.

Tissue specificity

Widely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine.

Cellular localization

  • Cytoplasm
  • Cytoskeleton
  • Microtubule organizing center
  • Centrosome
  • Centriole
  • Cell projection
  • Cilium
  • Cytoplasm
  • Cytoskeleton
  • Cilium basal body
  • Cytoplasm
  • Cytoskeleton
  • Microtubule organizing center
  • Centrosome
  • Cytoplasmic granule
  • Cytoplasm
  • Cytoskeleton
  • Microtubule organizing center
  • Centrosome
  • Centriolar satellite
  • Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951).

Alternative names

C16orf63, FOPNL, FOR20, PHSECRG2, CEP20, Centrosomal protein 20, FGFR1OP N-terminal-like protein, FOP-related protein of 20 kDa, LisH domain-containing protein FOPNL

Target type

Proteins

Molecular weight

19778Da

We found 1 product in 1 category

Proteins & Peptides

Target

Species of origin

Search our catalogue for 'FOPNL' (1)

Products