CEP70
Domain
The coiled-coil domains may be important for tubulin-gamma-binding and hence for centrosomal localization.
Function
Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Localized at the center of the radial microtubule array in interphase and at the spindle poles during various stages of mitosis.
Alternative names
BITE, CEP70, Centrosomal protein of 70 kDa, Cep70, p10-binding protein