CEP76
Developmental stage
Expressed at low level in G1 and is induced in S and G2 phase, during which point centrioles have already commenced duplication (at protein level).
Function
Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
Sequence Similarities
Belongs to the CEP76 family.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Centriole
- Does not localize along the ciliary axoneme.
Alternative names
C18orf9, CEP76, Centrosomal protein of 76 kDa, Cep76