CETN3
Function
Plays a fundamental role in microtubule-organizing center structure and function.
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.
Sequence Similarities
Belongs to the centrin family.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Nucleus
- Nucleolus
- Nucleus envelope
- Nucleus
- Nuclear pore complex
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Centriole
- Centrosome of interphase and mitotic cells (PubMed:9256449). Localizes to centriole distal lumen (PubMed:26337392). Localization at the nuclear pore complex requires NUP153 and TPR (PubMed:23591820).
Alternative names
CEN3, CETN3, Centrin-3