Cfd
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Post-translational modifications
N-glycosylated.
Sequence Similarities
Belongs to the peptidase S1 family.
Cellular localization
- Secreted
Alternative names
Adn, Df, Cfd, Complement factor D, 28 kDa adipocyte protein, Adipsin, C3 convertase activator, Properdin factor D