CFHR2
Function
Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Post-translational modifications
N-glycosylated.
Tissue Specificity
Expressed by the liver and secreted in plasma.
Cellular localization
- Secreted
Alternative names
CFHL2, FHR2, HFL3, CFHR2, Complement factor H-related protein 2, FHR-2, DDESK59, H factor-like 3, H factor-like protein 2