Cga
Developmental stage
Expressed in the ventral area of the anterior pituitary gland from 13.5 dpc onwards, expression remains at 18.5 dpc.
Function
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
Sequence Similarities
Belongs to the glycoprotein hormones subunit alpha family.
Cellular localization
- Secreted
Alternative names
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain, Luteinizing hormone alpha chain, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, Thyrotropin alpha chain, FSH-alpha, LSH-alpha, TSH-alpha, Cga