CHI3L2
Function
Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Sequence Similarities
Belongs to the glycosyl hydrolase 18 family.
Tissue Specificity
Highest expression in chondrocytes, followed by synoviocytes, lung and heart. Not detected in spleen, pancreas, and liver. May also be expressed in developing brain and placenta.
Cellular localization
- Secreted
Alternative names
Chitinase-3-like protein 2, Chondrocyte protein 39, YKL-39, CHI3L2