Chitotriosidase-1
Function
Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.
Sequence Similarities
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
Tissue Specificity
Detected in spleen. Secreted by cultured macrophages.
Cellular localization
- Secreted
- Lysosome
- A small proportion is lysosomal.
Alternative names
Chitotriosidase-1, Chitinase-1, CHIT1