CHPF2
Function
Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity.
Sequence Similarities
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
Tissue Specificity
Ubiquitous. Highly expressed in placenta, small intestine and pancreas.
Cellular localization
- Golgi apparatus
- Golgi stack membrane
- Single-pass type II membrane protein
Alternative names
CHSY3, CSGLCAT, KIAA1402, UNQ299/PRO339, CHPF2, Chondroitin sulfate glucuronyltransferase, CSGlcA-T, Chondroitin glucuronyltransferase, Chondroitin polymerizing factor 2, Chondroitin synthase 3, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase, ChPF-2, ChSy-3