Detected at high levels in 7 dpc mouse embryos; its level decreases at later developmental stages and in adult tissues.
Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
Cleaved by tolloid proteases; cleavage participates in dorsoventral patterning during early development.
Belongs to the chordin family.
Chordin, Chrd
Proteins
Oncology
We found 5 products in 2 categories
ab267579