CHRM5

Function

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.

Cellular localization

• Cell membrane
• Multi-pass membrane protein
• Cell junction
• Synapse
• Postsynaptic cell membrane
• Multi-pass membrane protein

Alternative names

• Muscarinic acetylcholine receptor M5
• CHRM5

Database links

• entrezGene:1133
• omim:118496
• swissprot:P08912

Target type

Proteins

Molecular weight

60074Da