Ckm

Function

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Sequence similarities

Belongs to the ATP:guanido phosphotransferase family.

Cellular localization

• Cytoplasm

Alternative names

• CKMM
• CKMM
• CKM
• Creatine kinase M-type
• Creatine kinase M chain
• Creatine phosphokinase M-type
• M-CK
• CPK-M

Database links

• entrezGene:1158
• entrezGene:1152
• omim:123310
• swissprot:P06732
• swissprot:P12277

Target type

Proteins

Primary research area

Metabolism

Molecular weight

43101Da