CKMT1A

Function

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Sequence Similarities

Belongs to the ATP:guanido phosphotransferase family.

Cellular localization

• Mitochondrion inner membrane
• Peripheral membrane protein
• Intermembrane side

Alternative names

CKMT, CKMT1B, CKMT1A, Acidic-type mitochondrial creatine kinase, Ubiquitous mitochondrial creatine kinase, Mia-CK, U-MtCK

Database links

swissprot:P12532 omim:123290 entrezGene:548596 omim:613415 entrezGene:1159