Cldn3
Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Sequence Similarities
Belongs to the claudin family.
Tissue Specificity
Expressed in the lung (PubMed:24588076, PubMed:9892664). Expressed at high levels in the liver and at lower levels, in kidney and testis (PubMed:9892664).
Cellular localization
- Cell junction
- Tight junction
- Cell membrane
- Multi-pass membrane protein
Alternative names
Cpetr2, Cldn3, Claudin-3, Clostridium perfringens enterotoxin receptor 2, CPE-R 2, CPE-receptor 2