CLDN6
Function
Plays a major role in tight junction-specific obliteration of the intercellular space.
(Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.
Sequence Similarities
Belongs to the claudin family.
Tissue Specificity
Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.
Cellular localization
- Cell junction
- Tight junction
- Cell membrane
- Multi-pass membrane protein
Alternative names
UNQ757/PRO1488, CLDN6, Claudin-6, Skullin