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Function

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Sequence similarities

Belongs to the claudin family.

Tissue specificity

Expressed mostly in embryonic tissues.

Cellular localization

  • Cell junction
  • Tight junction
  • Cell membrane
  • Multi-pass membrane protein

Alternative names

Claudin-6, Skullin, Lern1, Lingo1, Lrrn6a

Target type

Proteins

Primary research area

Oncology

Molecular weight

23388Da

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