CLEC1B

C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN. After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2.

Glycosylated.

Phosphorylated on tyrosine residue in response to rhodocytin binding.

Hematopoietic cells, megakaryocytes and platelets.

• Membrane
• Single-pass type II membrane protein

Clec2, Clec1b, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2

• entrezGene:56760
• swissprot:Q9JL99

Proteins

Immunology & Infectious Disease

26239Da