CLEC3B
Function
Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. Plays a role in retinal function (PubMed:35331648).
Involvement in disease
Macular dystrophy, retinal, 4
MCDR4
An autosomal dominant retinal disease characterized by late-onset macular degeneration, with multiple drusen-like deposits, macular geographic atrophy, and choroidal neovascularization. Patients also exhibit extensive retinal dysfunction with impaired rod function.
None
The disease is caused by variants affecting the gene represented in this entry.
Tissue Specificity
Found in plasma.
Cellular localization
- Secreted
Alternative names
TNA, CLEC3B, Tetranectin, TN, C-type lectin domain family 3 member B, Plasminogen kringle 4-binding protein