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Clec3b

Developmental stage

Highly expressed in the developing retina, at least since 13.5 dpc. Expression decreases afterwards and peaks again at postnatal day 14, and remains constantly expressed in the retina until adulthood.

Function

Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis (By similarity). Plays a role in retinal function (By similarity).

Tissue Specificity

Highest expression in lung, skeletal muscle and heart (PubMed:7835708, PubMed:8563165). Expressed in retina (PubMed:35331648).

Cellular localization

Alternative names

Tna, Clec3b, Tetranectin, TN, C-type lectin domain family 3 member B, Plasminogen kringle 4-binding protein

swissprot:P43025 entrezGene:21922