CLECL1P
Function
May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response.
Tissue Specificity
Expressed in spleen, lymph node, and tonsil. Lower expression in peripheral blood, bone marrow, and colon. No expression detected in thymus. Highly expressed in dendritic and B-cells.
Cellular localization
- Cell membrane
- Single-pass type II membrane protein
Alternative names
CLECL1, DCAL1, CLECL1P, Putative C-type lectin-like domain family 1, C-type lectin-like domain family 1 pseudogene, Dendritic cell-associated lectin 1, DC-associated lectin-1, DCAL-1