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CNN1

Function

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).

Sequence Similarities

Belongs to the calponin family.

Tissue Specificity

Smooth muscle, and tissues containing significant amounts of smooth muscle.

Alternative names

Calponin-1, Basic calponin, CNN1

swissprot:P51911 entrezGene:1264 omim:600806