Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses.
Belongs to the canopy family.
Prat4a, Tnrc5, Cnpy3, Protein canopy homolog 3, Protein associated with Tlr4, Trinucleotide repeat-containing gene 5 protein
Proteins
Immunology & Infectious Disease
30538Da
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